S. thermodepolymerans KpsM-KpsE in Glycolipid 1 state with rigid body fitted KpsT

(2R,5S,8S)-2,5-dihydroxy-5,10-dioxo-8-[(undecanoyloxy)methyl]-4,6,9-trioxa-5lambda~5~-phosphahenicosan-1-yl 3-deoxy-alpha-L-altro-oct-2-ulopyranosidonic acid

Molecular insights into capsular polysaccharide secretion.

ABC transporter KpsMT in complex with polysaccharide co-polymerase KpsE bound to the glycolipid in state 1

MIELRNLTKWYPTPHGRRYVFRNLNFRFPDDVSIGLIGRNGAGKSTLMRLLGGIEAPNEGEVVTDVSISWPVGLSGGFQG
SLTARENVKFVCRIYGTSHEDMLRKVRFVEEFAEIGEHFDLPMKTYSSGMRSRVAFGLSMAFDFDYYLIDEAMAVGDAQF
RAKSRAVFDSRVGQANMILVSHNMNDIKEYCDVVVLVDQGQATLYEDVEAGIAAYQGSLKKAAAKPDYKDDDDK

MGKIHLAVSERSPRVKRSPWQIQQAVLFALFLRELKTRLGGRWLGVFWVLLEPVAHIAVMTTLFSLAHRAAMPSIEYPVF
LITGLIPFFMFRGLVTRLMEAIDSNRGLFAYRQVKPIDTVIARAMLEISLQSIVYLIALGTLGWLGFHFLPVRALELAGV
SAVLIMLGASLGLFFAVVTNEIPQARAIVRISLLPLYFVSGVIFPVHTIPPQYLPLLQLNPVLHLIELSRASFFPQYRVL
QGINLAYPAGFALLSLFLALMLYRLRRHQLASVV

MGKIHMKLVSRLTAKRLQWALVYLPMLVATVYFLVFSADRYVSESVITVRQTSSNAPTGGMSGAALLLAGLTPASREDTC
YLQTYIHSMGLLQKLDQQLKLREHFGTPLRDPLFRLWGGTSQEWFLEYYRSRVEVLMDDICGLLTVRVQGFEPEFAQALN
RAILEESERFVNELSHRMAREQGQFAEAELERATARLQEAKRQLIAFQAKHKLLDPLAQAQATGTLTAELQAALTRQEAE
LRNALTYLNEDSYQVKALRSQINALRQQIDEERLRATAGKNGDRINAVAAEFHDLQLQVGFAEDAYKLALAAVESARIEA
TRKLKSLVVVEPPVLPEIAEYPRRWYNLATLLVVCCLIYGVVSLVVATIRDHQDGSGSGSHHHHHHHHHH

National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)

S. thermodepolymerans KpsMT-KpsE with bound glycolipid - state 1

ABC transporter, Capsular polysaccharide, MEMBRANE PROTEIN

MIELRNLTKWYPTPHGRRYVFRNLNFRFPDDVSIGLIGRNGAGKSTLMRLLGGIEAPNEGEVVTDVSISWPVGLSGGFQG
SLTARENVKFVCRIYGTSHEDMLRKVRFVEEFAEIGEHFDLPMKTYSSGMRSRVAFGLSMAFDFDYYLIDEAMAVGDAQF
RAKSRAVFDSRVGQANMILVSHNMNDIKEYCDVVVLVDQGQATLYEDVEAGIAAYQGSLKKAAAKP

AVSERSPRVKRSPWQIQQAVLFALFLRELKTRLGGRWLGVFWVLLEPVAHIAVMTTLFSLAHRAAMPSIEYPVFLITGLI
PFFMFRGLVTRLMEAIDSNRGLFAYRQVKPIDTVIARAMLEISLQSIVYLIALGTLGWLGFHFLPVRALELAGVSAVLIM
LGASLGLFFAVVTNEIPQARAIVRISLLPLYFVSGVIFPVHTIPPQYLPLLQLNPVLHLIELSRASFFPQYRVLQGINLA
YPAGFALLSLFLALMLYRLRRHQLASVV

MKLVSRLTAKRLQWALVYLPMLVATVYFLVFSADRYVSESVITVRQTSSNAPTGGMSGAALLLAGLTPASREDTLYLQTY
IHSMGLLQKLDQQLKLREHFGTPLRDPLFRLWGGTSQEWFLEYYRSRVEVLMDDISGLLTVRVQGFEPEFAQALNRAILE
ESERFVNELSHRMAREQGQFAEAELERATARLQEAKRQLIAFQAKHKLLDPLAQAQATGTLTAELQAALTRQEAELRNAL
TYLNEDSYQVKALRSQINALRQQIDEERLRATAGKNGDRINAVAAEFHDLQLQVGFAEDAYKLALAAVESARIEATRKLK
SLVVVEPPVLPEIAEYPRRWYNLATLLVVCCLIYGVVSLVVATIRDHQD