Molecular insights into capsular polysaccharide secretion.

ABC transporter KpsMT in complex with polysaccharide co-polymerase KpsE in Apo 1 state

MIELRNLTKWYPTPHGRRYVFRNLNFRFPDDVSIGLIGRNGAGKSTLMRLLGGIEAPNEGEVVTDVSISWPVGLSGGFQG
SLTARENVKFVCRIYGTSHEDMLRKVRFVEEFAEIGEHFDLPMKTYSSGMRSRVAFGLSMAFDFDYYLIDEAMAVGDAQF
RAKSRAVFDSRVGQANMILVSHNMNDIKEYCDVVVLVDQGQATLYEDVEAGIAAYQGSLKKAAAKPDYKDDDDK

MGKIHLAVSERSPRVKRSPWQIQQAVLFALFLRELKTRLGGRWLGVFWVLLEPVAHIAVMTTLFSLAHRAAMPSIEYPVF
LITGLIPFFMFRGLVTRLMEAIDSNRGLFAYRQVKPIDTVIARAMLEISLQSIVYLIALGTLGWLGFHFLPVRALELAGV
SAVLIMLGASLGLFFAVVTNEIPQARAIVRISLLPLYFVSGVIFPVHTIPPQYLPLLQLNPVLHLIELSRASFFPQYRVL
QGINLAYPAGFALLSLFLALMLYRLRRHQLASVV

MGKIHMKLVSRLTAKRLQWALVYLPMLVATVYFLVFSADRYVSESVITVRQTSSNAPTGGMSGAALLLAGLTPASREDTC
YLQTYIHSMGLLQKLDQQLKLREHFGTPLRDPLFRLWGGTSQEWFLEYYRSRVEVLMDDICGLLTVRVQGFEPEFAQALN
RAILEESERFVNELSHRMAREQGQFAEAELERATARLQEAKRQLIAFQAKHKLLDPLAQAQATGTLTAELQAALTRQEAE
LRNALTYLNEDSYQVKALRSQINALRQQIDEERLRATAGKNGDRINAVAAEFHDLQLQVGFAEDAYKLALAAVESARIEA
TRKLKSLVVVEPPVLPEIAEYPRRWYNLATLLVVCCLIYGVVSLVVATIRDHQDGSGSGSHHHHHHHHHH

National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)

ABC transporter, Capsular polysaccharide, MEMBRANE PROTEIN

MIELRNLTKWYPTPHGRRYVFRNLNFRFPDDVSIGLIGRNGAGKSTLMRLLGGIEAPNEGEVVTDVSISWPVGLSGGFQG
SLTARENVKFVCRIYGTSHEDMLRKVRFVEEFAEIGEHFDLPMKTYSSGMRSRVAFGLSMAFDFDYYLIDEAMAVGDAQF
RAKSRAVFDSRVGQANMILVSHNMNDIKEYCDVVVLVDQGQATLYEDVEAGIAAYQGSLKKAAAKP

AVSERSPRVKRSPWQIQQAVLFALFLRELKTRLGGRWLGVFWVLLEPVAHIAVMTTLFSLAHRAAMPSIEYPVFLITGLI
PFFMFRGLVTRLMEAIDSNRGLFAYRQVKPIDTVIARAMLEISLQSIVYLIALGTLGWLGFHFLPVRALELAGVSAVLIM
LGASLGLFFAVVTNEIPQARAIVRISLLPLYFVSGVIFPVHTIPPQYLPLLQLNPVLHLIELSRASFFPQYRVLQGINLA
YPAGFALLSLFLALMLYRLRRHQLASVV

MKLVSRLTAKRLQWALVYLPMLVATVYFLVFSADRYVSESVITVRQTSSNAPTGGMSGAALLLAGLTPASREDTLYLQTY
IHSMGLLQKLDQQLKLREHFGTPLRDPLFRLWGGTSQEWFLEYYRSRVEVLMDDISGLLTVRVQGFEPEFAQALNRAILE
ESERFVNELSHRMAREQGQFAEAELERATARLQEAKRQLIAFQAKHKLLDPLAQAQATGTLTAELQAALTRQEAELRNAL
TYLNEDSYQVKALRSQINALRQQIDEERLRATAGKNGDRINAVAAEFHDLQLQVGFAEDAYKLALAAVESARIEATRKLK
SLVVVEPPVLPEIAEYPRRWYNLATLLVVCCLIYGVVSLVVATIRDHQD