CryoEM structure of H7 hemagglutinin from A/Shanghai2/2013 H7N9 in complex with a human neutralizing antibody H7.HK1

N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE

H7 hemagglutinin from A/Shanghai2/2013 H7N9 in complex with a human neutralizing antibody H7.HK1

H7.HK1 Neutralizing Antibody Heavy Chain

QVQLQESGPGLVKPSETLSLTCSVSGGSINSYYWTWIRQPPGKGLEWVGYIYHSGSTSYNPSLKSRITISVAPSKNHFSL
ELTSMTAADTAVYYCARLGGHGDYGSDYWGQGTLVTVSS

DIVMTQSPVSLPVTPGEPASISCNSSQSLLHSNGYAHLDWYLQKPGQSPKLMIYLGLNRAFGVPDRFSGSGSGTDFTLKI
SRVEAEDVGVYYCMQALQTPFTFGPGTRVDIK

MNTQILVFALIAIIPTNADKICLGHHAVSNGTKVNTLCERGVEVVNATETVERTNIPRICSKGKRTVDLGQCGLLGTITG
PPQCDQFLEFSADLIIERREGSDVCYPGKFVNEEALRQILRESGGIDKEAMGFTYSGIRTNGATSSCRRSGSSFYAEMKW
LLSNTDNAAFPQMTKSYKNTRKNPALIVWGIHHSGSTAEQTKLYGSGNKLVTVGSSNYQQSFVPSPGARTQVNGQSGRID
FHWLMLNPNDTVTFSFNGAFIAPDRASFLRGKSMGIQSGVQVDADCEGDCYYSGGTIISNLPFQNIDSRAVGKCPRYVKQ
RSLLLATGMKNVPEIPKGRRRRRRGLFGAIAGFIENGWEGLIDGWYGFRHQNAQGEGTAADYKSTQSAIDCITGKLNRLI
EKTNQQFELIDNEFTEVEKQIGNVINWTRDSITEVWSYNAELLVAMENQHTIDLADSEMDKLYERVKRQLRENAEEDGTG
CFEIFHKCDDDCMASIRNNTYDHSKYREEAMQNRIQIDGVSGRLVPRGSPGSGYIPEAPRDGQAYVRKDGEWVLLSTFLG
HHHHHH

Influenza A virus (A/Shanghai/02/2013(H7N9))

virus, antibody, influenza, VIRAL PROTEIN, VIRAL PROTEIN-IMMUNE SYSTEM complex

MNTQILVFALIAIIPTNADKICLGHHAVSNGTKVNTLTERGVEVVNATETVERTNIPRICSKGKRTVDLGQCGLLGTITG
PPQCDQFLEFSADLIIERREGSDVCYPGKFVNEEALRQILRESGGIDKEAMGFTYSGIRTNGATSACRRSGSSFYAEMKW
LLSNTDNAAFPQMTKSYKNTRKNPALIVWGIHHSGSTAEQTKLYGSGNKLVTVGSSNYQQSFAPSPGARTQVNGQSGRID
FHWLMLNPNDTVTFSFNGAFIAPDRASFLRGKSMGIQSGVQVDADCEGDCYHSGGTIISNLPFQNIDSRAVGKCPRYVKQ
RSLLLATGMKNVPEIPKGRGLFGAIAGFIENGWEGLIDGWYGFRHQNAQGEGTAADYKSTQSAIDQITGKLNRLIEKTNQ
QFELIDNEFTEVEKQIGNVINWTRDSITEVWSYNAELLVAMENQHTIDLADSEMDKLYERVKRQLRENAEEDGTGCFEIF
HKCDDDCMASIRNNTYDHSKYREEAMQNRIQIDPV