Crystal structure of human FAD synthase PAPS domain in complex with FAD

2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.

Structural insights into the bifunctional enzyme human FAD synthase.

FAD pyrophosphorylase,FMN adenylyltransferase,Flavin adenine dinucleotide synthase

GSHMPNAVEQASEAVYKLAESGSSLGKKVAGALQTIETSLAQYSLTQLCVGFNGGKDCTALLHLFHAAVQRKLPDVPNPL
QILYIRSISPFPELEQFLQDTIKRYNLQMLEAEGSMKQALGELQARHPQLEAVLMGTRRTDPYSCSLCPFSPTDPGWPAF
MRINPLLDWTYRDIWDFLRQLFVPYCILYDRGYTSLGSRENT

Ministero dell Universita e della Ricerca

Human FAD synthase, FAD synthesis, FAD hydrolysis, bifunctional protein, FLAVOPROTEIN

MPNAVEQASEAVYKLAESGSSLGKKVAGALQTIETSLAQYSLTQLCVGFNGGKDCTALLHLFHAAVQRKLPDVPNPLQIL
YIRSISPFPELEQFLQDTIKRYNLQMLEAEGSMKQALGELQARHPQLEAVLMGTRRTDPYSCSLCPFSPTDPGWPAFMRI
NPLLDWTYRDIWDFLRQLFVPYCILYDRGYTSLGSRENT