Crystal structure of the kelch domain of human KLHL12 in complex with PLEKHA4 peptide

2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.

Pleckstrin homology domain-containing family A member 4 (PLEKHA4) 11-mer peptide
Pleckstrin homology domain-containing family A member 4

CUL3-interacting protein 1,DKIR homolog,hDKIR

PH domain-containing family A member 4,Phosphoinositol 3-phosphate-binding protein 1,PEPP-1

SMQGPRTRARLGANEVLLVVGGFGSQQSPIDVVEKYDPKTQEWSFLPSITRKRRYVASVSLHDRIYVIGGYDGRSRLSSV
ECLDYTADEDGVWYSVAPMNVRRGLAGATTLGDMIYVSGGFDGSRRHTSMERYDPNIDQWSMLGDMQTAREGAGLVVASG
VIYCLGGYDGLNILNSVEKYDPHTGHWTNVTPMATKRSGAGVALLNDHIYVVGGFDGTAHLSSVEAYNIRTDSWTTVTSM
TTPRCYVGATVLRGRLYAIAGYDGNSLLSSIECYDPIIDSWEVVTSMGTQRCDAGVCVLRE

0.1 M citrate pH 5.5, 0.4 M NaCl,
27,1% PEG8K

Biotechnology and Biological Sciences Research Council (BBSRC)

Inhibitor, Complex, Ligase, Interaction Motif, KLHL12, PLEKHA4

MQGPRTRARLGANEVLLVVGGFGSQQSPIDVVEKYDPKTQEWSFLPSITRKRRYVASVSLHDRIYVIGGYDGRSRLSSVE
CLDYTADEDGVWYSVAPMNVRRGLAGATTLGDMIYVSGGFDGSRRHTSMERYDPNIDQWSMLGDMQTAREGAGLVVASGV
IYCLGGYDGLNILNSVEKYDPHTGHWTNVTPMATKRSGAGVALLNDHIYVVGGFDGTAHLSSVEAYNIRTDSWTTVTSMT
TPRCYVGATVLRGRLYAIAGYDGNSLLSSIECYDPIIDSWEVVTSMGTQRCDAGVCVLRE