Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains

2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.

1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.

ALEKDRRALEALKRAQEAEKKGDVEEAVRAAQEAVRAAKESGASWILRLVAEQALRIAKEAEKQGNVEVAVKAARVAVEA
AKQAGDNDVLRKVAEQALRIAKEAEKQGNVDVAAKAAQVAAEAAKQAGDKDMLEKVAKVAEQIAKAAEKEGDKKVSIDAT
RIALEASLAALEIILEELKEMLERLEKNPDKDVIVKVLKVIVKAIEASVKNQKISAKNQKALAELA

designed protein, protein assemblies, negative design, cryptic transmembrane domains, DE NOVO PROTEIN