Crystal structure of Ky15.10 Fab in complex with circumsporozoite protein DND peptide

2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.

Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein.

QVQLVESGGGVVQPGRSLRLSCAASGFTFSNSGMHWVRQVPGKGLEWVAIIWYDGSNKYYADSVKGRFSVSRDNSENTLY
LQMSNLRAEDTAVYYCVRAYFDSENLYDYYGMDVWGQGTTVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPE
PVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC

DIQMTQSPSTLSASVGDRVTITCRASQSISRWLAWFQKKPGKAPKLLIYTASNLESGVPSRFSGSGSGTEFTLTISSLQP
DDFATYYCQQYYNYWTFGQGTKVEVKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQE
SVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC

0.2 M ammonium acetate, 0.1 M HEPES pH 7.5, 25% PEG3350