Structure of VanS from vancomycin-resistant enterococci: A sensor kinase with weak ATP binding.
Vancomycin histidine protein kinase,Vancomycin resistance protein VanS
NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFNNILKNAAAYSEDNSIIDITAGL SGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSSDTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDL VDKRRS
Protein and precipitant were mixed in a volume ratio of 1:2 and incubated under Als Oil at 291K; the precipitant solution was obtained from the Berkeley Screen and contained 75 mM Bis-Tris Propane, 25 mM citric acid, pH 8.2, 20 mM CdCl2, and 25 (w-v) PEG 400.
National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)
ATP-binding, histidine kinase, SIGNALING PROTEIN