PBP AccA from A. vitis S4 in complex with Agrocinopine D-like

Agrocinopine D-like (C2-C2 linked; with two alpha-D-glucopyranoses)
Agrocinopine D-like; bis[(2S,3R,4S,5S,6R)-6-(hydroxymethyl)-2,4,5-tris(oxidanyl)oxan-3-yl] hydrogen phosphate; D-glucose-2-phosphate-2-glucose

A highly conserved ligand-binding site for AccA transporters of antibiotic and quorum-sensing regulator in Agrobacterium leads to a different specificity.

Agrocinopine utilization periplasmic binding protein AccA

ABC transporter substrate binding protein (Agrocinopine)

SAERRALKIGVNGIPVTLEPINAISNVGPRIVNQIFDTLVVRDFFSNGAPGNGINLMPSLAESWERIDDKSVRFKLRQKV
MFHDGVEMTADDVAYTFSSERLWGPDAIKVIPLGGSYALDFDEPVVEDKYTVVIRTKTPTPLTESYMASWMGRIVPKAYY
KTLGTAAFGNKPVGTGPYKFVEFVANDRVVIEANDAYWGLKPTASKITYQLVAEPATRVAGLISGEYDIVTTLTPDDMAL
INSYPDLETRGNIVENFHMFTFNMNQPVFQSKPLRRALALAVNRPLIVQSLWMNKATIPNGFNFPNYGKTFDPNRRAMEY
NIEEAKRLVKESGYDGTPITYHTMGNYYANAVPALMMMIEMWKQIGVTVVPKVYAPGGAPKDQDSYMRNWSNGQWMTDAW
ATMICEFGPKGQVQKRWGWKAPAEFNDLCTKVSQIPDSKERFDAFNRLRDIFEEEAPAVILYQPFDVYAARKDVHWRPIS
FEMMEFRNNLAFGHHHHHH

Escherichia coli 'BL21-Gold(DE3)pLysS AG'

periplasmic binding protein, solute binding protein, TRANSPORT PROTEIN