An i-motif domain able to undergo pH-dependent conformational transitions (acidic structure)
2'-DEOXY-N3-PROTONATED CYTIDINE-5'-MONOPHOSPHATE
pH-Dependent Capping Interactions Induce Large-Scale Structural Transitions in i-Motifs.
DNA (5'-D(*CP*(DNR)P*GP*TP*TP*(DNR)P*(DNR)P*GP*TP*TP*TP*TP*TP*CP*CP*GP*TP*TP*(DNR)P*CP*GP*T)-3')
(DC)(DNR)(DG)(DT)(DT)(DNR)(DNR)(DG)(DT)(DT)(DT)(DT)(DT)(DC)(DC)(DG)(DT)(DT)(DNR) (DC)(DG)(DT)
Spanish Ministry of Science, Innovation, and Universities
500 uM DNA (5'-D(*CP*(DNR)P*GP*TP*TP*(DNR)P*(DNR)P*GP*TP*TP*TP*TP*TP*CP*CP*GP*TP*TP*(DNR)P*CP*GP*T)-3'), 10 mM sodium phosphate, 0.5 v/v DSS, 90% H2O/10% D2O
500 uM DNA (5'-D(*CP*(DNR)P*GP*TP*TP*(DNR)P*(DNR)P*GP*TP*TP*TP*TP*TP*CP*CP*GP*TP*TP*(DNR)P*CP*GP*T)-3'), 10 mM sodium phosphate, 0.5 v/v DSS, 100% D2O
Case, Darden, Cheatham III, Simmerling, Wang, Duke, Luo, ... and Kollman