Crystal structure of CUG repeat RNA duplex containing U-U mismatches
Structural basis for water modulating RNA duplex formation in the CUG repeats of myotonic dystrophy type 1.
RNA (5'-R(P*UP*UP*CP*UP*GP*CP*UP*GP*CP*UP*GP*AP*A)-3')
0.4 mM oligonucleotide, 3.5 mM Spermine tetrahydrochloride, 50 mM HEPES pH 6.5, 10% MPD
Ministry of Science and Technology (MoST, Taiwan)
CUG repeats, U-U mismatch, Myotonic dystrophy type 1 (DM1), Water mediated U-U mismatch, RNA