Crystal structure of the Human TR4 DNA-Binding Domain Homodimer Bound to DR1 Response Element

Structures of human TR4LBD-JAZF1 and TR4DBD-DNA complexes reveal the molecular basis of transcriptional regulation.

Nuclear receptor subfamily 2 group C member 2

DNA (5'-D(*GP*GP*CP*AP*GP*AP*GP*GP*TP*CP*AP*AP*AP*GP*GP*TP*CP*A)-3')

DNA (5'-D(*CP*TP*GP*AP*CP*CP*TP*TP*TP*GP*AP*CP*CP*TP*CP*TP*GP*C)-3')

Orphan nuclear receptor TAK1,Orphan nuclear receptor TR4,Testicular receptor 4

Escherichia coli 'BL21-Gold(DE3)pLysS AG'

PEG4000, sodium citrate, ammonium acetate

National Natural Science Foundation of China (NSFC)

Hydrogens have been added in their riding positions

Transcriptional regulation, DNA BINDING, PROTEIN-DNA COMPLEX, DNA BINDING PROTEIN-DNA complex