Crystal structure of Fab region of TAU-2212 neutralizing SARS-CoV-2

2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.

1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.

Conformational flexibility in neutralization of SARS-CoV-2 by naturally elicited anti-SARS-CoV-2 antibodies.

MGWSCIILFLVATATGVHSQVQLVQSGAEVKKPGASVKVSCKASGYTFTGYYMHWVRQAPGQGLEWMGWINPNSGGTNYA
QKFQGWVTMTRDTSISTAYMELSRLRSDDTAVYYCARGWATYYDILTGYSLFDYWGQGTLVTVSSASTKGPSVFPLAPSS
KSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVD
KRVEPKSCDKGS

MGWSCIILFLVATATGSWAQSALTQPASVSGSPGQSITISCTGTSSDVGSYNLVSWYQQHPGKAPKLMIYEVSKRPSGVS
NRFSGSKSGNTASLTISGLQAEDEADYYCCSYAGSSTPHVVFGGGTKLTVLGQPKAAPSVTLFPPSSEELQANKATLVCL
ISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTECS

26% (w/v) polyethylene glycol 3350, 0.2 M (NH4)2SO4, pH 8.0

National Natural Science Foundation of China (NSFC)

Hydrogens have been used if present in the input file

Local NCS retraints between domains: 1 2

Local NCS retraints between domains: 3 4