Solution NMR structure of 8-residue Rosetta-designed cyclic peptide D8.21 in d6-DMSO with cis/trans switching
Accurate de novo design of membrane-traversing macrocycles.
Cyclic peptide D8.21 DVA-MLE-DPR-LEU-DVA-MLE-DPR-LEU
National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)
D8.21. 8-residue cyclic peptide with (trans-trans) symmetric conformation in d6-DMSO. TT symmetric conformation has trans DPR3 and trans DPR7
Delaglio, Grzesiek, Vuister, Zhu, Pfeifer and Bax
Tejero, Snyder, Mao, Aramini, Montelione
cyclic peptide, non natural amino acids, cis/trans, switch peptides, de novo design, membrane permeability, DE NOVO PROTEIN