Crystal Structure of KPC-2 with compound 2

Probing the binding hot spots of KPC-2 carbapenemase using reversible tetrazole-based inhibitors

Carbapenem-hydrolyzing beta-lactamase KPC

Carbapenem-hydrolyzing beta-lactamase KPC-1

TNLVAEPFAKLEQDFGGSIGVYAMDTGSGATVSYRAEERFPLCSSFKGFLAAAVLARSQQQAGLLDTPIRYGKNALVPWS
PISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGPAGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAV
TESLQKLTLGSALAAPQRQQFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGVYGTANDYAVVWPTGRAPIVLAVYTRA
PNKDDKHSEAVIAAAARLALEGLGV

National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)

beta-lactamase, tetrazole, inhibitor, complex, HYDROLASE, HYDROLASE-HYDROLASE inhibitor complex