Heterodimeric complex of Pf12 and Pf41 of Plasmodium falciparum

N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE

Structure of the Pf12 and Pf41 heterodimeric complex of Plasmodium falciparum 6-cysteine proteins.

GASKSHKCDFTKEKYLLSGEKEVSCEIDANPSDDITFICPNKIDSLCFHTVNISKNINQNKSTMSIQDLLYGSVVYGNTL
FISPYVRTNTPFYCFCNLDTVTIQKFLKINRFLKDDDELSEADVMKHLKGGNVSEAQADEYLNKALNRFKKMKDLSKFFN
DQADNTTKLNLPKSLNIPNDILNYDVYNSSNNRNDIVVKDEVTNKQIISKRGIMSVFVRSNNNVIKGCDFGNNNKNYFSH
PISVAGKVNNKVCKIQGKPGELVGFKCAFEENGKVEPPNCFDQVLHKNKVTDLKTLIPGYASYTNKHSSKYPYYLKIPHF
VNEQYTIQCKCKSNNSQNEYTFELDIQPGES

GASNLTCDFNDVYKLEFHPNQQTSVTKLCNLTPNVLEKVTIKCGSDKLNYNLYPPTCFEEVYASRNMMHLKKIKEFVIGS
SMFMRRSLTPNKINEVSFRIPPNMMPEKPIYCFCENKKTITINGSNGNPSSKKDIINRGIVEIIIPSLNEKVKGCDFTTS
ESTIFSKGYSINEISNKSSNNQQDIVCTVKAHANDLIGFKCPSNYSVEPHDCFVSAFNLSGKNENLENKLKLTNIIMDHY
NNTFYSRLPSLISDNWKFFCVCSKDNEKKLVFTVEASISS

10 mM cadmium chloride, 14% (w/v) PEG 4000, 25% glycerol, 50 mM HEPES pH 7.5

National Health and Medical Research Council (NHMRC, Australia)

analytical ultracentrifugation, binding and affinity determination using Bio-layer interferometry

6-cysteine protein, s48/45 domain, complex, heterodimer, UNKNOWN FUNCTION

SKSHKCDFTKEKYLLSGEKEVSCEIDANPSDDITFICPNKIDSLCFHTVNISKNINQNKSTMSIQDLLYGSVVYGNTLFI
SPYVRTNTPFYCFCNLDTVTIQKFLKINRFLKDDDELSEADVMKHLKGGNVSEAQADEYLNKALNRFKKMKDLSKFFNDQ
ADNTTKLNLPKSLNIPNDILNYDVYNSSNNRNDIVVKDEVTNKQIISKRGIMSVFVRSNNNVIKGCDFGNNNKNYFSHPI
SVAGKVNNKVCKIQGKPGELVGFKCAFEENGKVEPPNCFDQVLHKNKVTDLKTLIPGYASYTNKHSSKYPYYLKIPHFVN
EQYTIQCKCKSNNSQNEYTFELDIQPGES

NLTCDFNDVYKLEFHPNQQTSVTKLCNLTPNVLEKVTIKCGSDKLNYNLYPPTCFEEVYASRNMMHLKKIKEFVIGSSMF
MRRSLTPNKINEVSFRIPPNMMPEKPIYCFCENKKTITINGSNGNPSSKKDIINRGIVEIIIPSLNEKVKGCDFTTSEST
IFSKGYSINEISNKSSNNQQDIVCTVKAHANDLIGFKCPSNYSVEPHDCFVSAFNLSGKNENLENKLKLTNIIMDHYNNT
FYSRLPSLISDNWKFFCVCSKDNEKKLVFTVEASISS