Structure of the A-region of Awp14 from Candida glabrata

2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.

1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.

Structure of the cluster III adhesin Awp14 from a clinical isolate of Candida glabrata

Characterization of Awp14, A Novel Cluster III Adhesin Identified in a High Biofilm-Forming

A novel class of Candida glabrata cell wall proteins with beta-helix fold mediates adhesion in clinical isolates.

MGSSHHHHHHSSGLVPRGSHMASMTGGQQMGRGSKTYENQKIVIDGVALGTTTFEDDELLVLKNSTLTLNNFMNIKLPAG
ISLTDNSVLNINTPPDDTPPSDSYDVKRPQYSMVINGKVSIDNGSQFVFDGSSLVYSLGPYASEKFLFDINTGMDGIFIS
KDSTMRITLPKYLDWGFSHATTKFSGIHIGGTYKAPYNSPLVILGTLEVLRSDSRTDDGYFDDNLFRIDLGPDKIDENGV
FTMKNDLSGNIHCQGILSFFADIFKGTDNVFIRTIGFQAISPISPITVDLAEGPVQGNGYLRYNVIISQGQGNGLKLLNL
QARLDIGLPIIYIYNSDNYKDLTAKAHDNVIDIIDHSSNKSFSIIGDRKYNITYWYQQYTEIYPSYQYGGYFKVPLFKKS
LQLDFIPIIEPDY

0.1 M BES/TEA pH 7.5, 10% (w/v) PEG 8000, 20% 1,5-pentanediol, Amino-acid II (1:10) of Morpheus II

GPI-anchored cell wall protein, Candida glabrata, clinical isolate, beta-helix domain, CELL ADHESION

(chain "B" and ((resid 22 and (name N or name CA or name C or name O or name CB )) or resid 23 through 397))

KTYENQKIVIDGVALGTTTFEDDELLVLKNSTLTLNNFMNIKLPAGISLTDNSVLNINTPPDDTPPSDSYDVKRPQYSMV
INGKVSIDNGSQFVFDGSSLVYSLGPYASEKFLFDINTGMDGIFISKDSTMRITLPKYLDWGFSHATTKFSGIHIGGTYK
APYNSPLVILGTLEVLRSDSRTDDGYFDDNLFRIDLGPDKIDENGVFTMKNDLSGNIHCQGILSFFADIFKGTDNVFIRT
IGFQAISPISPITVDLAEGPVQGNGYLRYNVIISQGQGNGLKLLNLQARLDIGLPIIYIYNSDNYKDLTAKAHDNVIDII
DHSSNKSFSIIGDRKYNITYWYQQYTEIYPSYQYGGYFKVPLFKKSLQLDFIPIIEPDY