Crystal structure of Paradendryphiella salina PL7A alginate lyase in complex with di-mannuronic acid

2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.

beta-D-mannuronic acid; D-mannuronic acid; mannuronic acid; (2S,3S,4S,5S,6R)-3,4,5,6-tetrahydroxyoxane-2-carboxylic acid

alpha-D-mannuronic acid; D-mannuronic acid; mannuronic acid

beta-D-mannopyranuronic acid-(1-4)-alpha-D-mannopyranuronic acid

EFYTAPSTESKFTEVLSKAKLQYPTSTTVAFADDLLDGYAASYFYLTSDLYMQFQVAGSSQRSELREMETSGDEAAWDCT
GSTAHVASAQIAIPVQEDGIEEVTILQVHDSDVTPVLRISWVSSITIDGVTSEDVVLATIRNGIDDSTATKTVLQAHTTS
RTEFNINVQNSKLSITVDGTTELDEADISQFDGSTCYFKAGAYNNNPTDTSANARIKMYELEWVDHHHHHH

Y223F in complex with hexa-mannuronic acid

Y223F in complex with di-mannuronic acid

Y223F in complex with penta-mannuronic acid

Y223F in complex with tetra-mannuronic acid

Y223F in complex with tri-mannuronic acid

Native in complex with tri-mannuronic acid

Native in complex with hexa-mannuronic acid

Native in complex with penta-mannuronic acid

Native in complex with tetra-mannuronic acid

complex, beta jelly roll, mutant, alginate lyase, LYASE

YTAPSTESKFTEVLSKAKLQYPTSTTVAFADDLLDGYAASYFYLTSDLYMQFQVAGSSQRSELREMETSGDEAAWDCTGS
TAHVASAQIAIPVQEDGIEEVTILQVHDSDVTPVLRISWVSSITIDGVTSEDVVLATIRNGIDDSTATKTVLQAHTTSRT
EFNINVQNSKLSITVDGTTELDEADISQFDGSTCYFKAGAYNNNPTDTSANARIKMYELEW