NMR structure of the Bak transmembrane helix in DPC micelles
High-resolution analysis of the conformational transition of pro-apoptotic Bak at the lipid membrane.
Apoptosis regulator BAK,Bcl-2-like protein 7,Bcl2-L-7
400 uM [U-13C; U-15N; U-2H] Bak-TMH, 20 mM sodium phosphate, 50 mM sodium chloride, 0.5 mM EDTA, 5 mM DTT, 300 mM DPC, 95% H2O/5% D2O
2H,13C,15N-Bak-TMH in 300 mM DPC micelles
Schwieters, Kuszewski, Tjandra and Clore
mitochondria, pore formation, Bcl2 proteins, APOPTOSIS