Crystal structure of human mitochondrial ferritin (hMTF) Fe(II)-loaded for 5 minutes under anaerobic environment

Iron Binding in the Ferroxidase Site of Human Mitochondrial Ferritin.

MPAAGPSRVRQNFHPDSEAAINRQINLELYASYVYLSMAYYFSRDDVALNNFSRYFLHQSREETEHAEKLMRLQNQRGGR
IRLQDIKKPEQDDWESGLHAMECALLLEKNVNQSLLELHALASDKGDPHLCDFLETYYLNEQVKSIKELGDHVHNLVKMG
APDAGLAEYLFDTHTLGNENKQN

1.6-2 M MgCl2 6H2O and 0.1 M bicine pH 9.0

human mitochondrial ferritin, hMTF, time-controlled iron loading, ferroxidase site, oxidoreductase, anaerobic environment

PAAGPSRVRQNFHPDSEAAINRQINLELYASYVYLSMAYYFSRDDVALNNFSRYFLHQSREETEHAEKLMRLQNQRGGRI
RLQDIKKPEQDDWESGLHAMECALLLEKNVNQSLLELHALASDKGDPHLCDFLETYYLNEQVKSIKELGDHVHNLVKMGA
PDAGLAEYLFDTHTLGNENKQN