Mycobacterium smegmatis ATP synthase F1 state 2

Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis.

ATP synthase F1 sector subunit alpha,F-ATPase subunit alpha

ATP synthase F1 sector subunit beta,F-ATPase subunit beta

ATP synthase F1 sector gamma subunit,F-ATPase gamma subunit

MAELTISAADIEGAIEDYVSSFSADTEREEIGTVIDAGDGIAHVEGLPSVMTQELLEFPGGVLGVALNLDEHSVGAVILG
EFEKIEEGQQVKRTGEVLSVPVGDAFLGRVVNPLGQPIDGQGDIAAETRRALELQAPSVVQRQSVSEPLQTGIKAIDAMT
PIGRGQRQLIIGDRKTGKTAVCVDTILNQREAWLTGDPKQQVRCVYVAIGQKGTTIASVKRALEEGGAMEYTTIVAAPAS
DAAGFKWLAPYTGSAIGQHWMYNGKHVLIVFDDLSKQADAYRAISLLLRRPPGREAFPGDVFYLHSRLLERCAKLSDELG
GGSMTGLPIIETKANDISAFIPTNVISITDGQCFLESDLFNQGVRPAINVGVSVSRVGGAAQIKAMKEVAGSLRLDLSQY
RELEAFAAFASDLDAASKAQLDRGARLVELLKQPQYSPLAVEEQVVAIFLGTQGHLDSVPVEDVQRFESELLEHVKASHS
DIFDGIRETKKLSEEAEEKLVSVINEFKKGFQASDGSSVVVSENAEALDPEDLEKESVKVRKPAPKKA

MTATAEKTAGRVVRITGPVVDVEFPRGSVPELFNALHAEITFGALAKTLTLEVAQHLGDSLVRCISMQPTDGLVRGVEVT
DTGASISVPVGDGVKGHVFNALGDCLDDPGYGKDFEHWSIHRKPPAFSDLEPRTEMLETGLKVVDLLTPYVRGGKIALFG
GAGVGKTVLIQEMINRIARNFGGTSVFAGVGERTREGNDLWVELADANVLKDTALVFGQMDEPPGTRMRVALSALTMAEF
FRDEQGQDVLLFIDNIFRFTQAGSEVSTLLGRMPSAVGYQPTLADEMGELQERITSTRGRSITSMQAVYVPADDYTDPAP
ATTFAHLDATTELSRAVFSKGIFPAVDPLASSSTILDPAIVGDEHYRVAQEVIRILQRYKDLQDIIAILGIDELSEEDKQ
LVNRARRIERFLSQNMMAAEQFTGQPGSTVPLKETIEAFDKLTKGEFDHLPEQAFFLIGGLDDLAKKAESLGAKL

MAATLRELRGRIRSAGSIKKITKAQELIATSRIAKAQARVEAARPYAAEITNMLTELAGASALDHPLLVERKQPKRAGVL
VVSSDRGLCGAYNANVLRRAEELFSLLRDEGKDPVLYVVGRKALGYFSFRQRTVVESWTGFSERPTYENAREIADTLVNA
FMAGADDEGDDAGADGILGVDELHIVFTEFRSMLSQTAVARRAAPMEVEYVGEVETGPRTLYSFEPDPETLFDALLPRYI
ATRVYAALLEAAASESASRRRAMKSATDNADDLIKALTLAANRERQAQITQEISEIVGGANALAGSK

Medical Research Council (MRC, United Kingdom)