Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment, C102

2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.

SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.

QVQLVESGGGLIQPGGSLRLSCAASGFIVSSNYMSWVRQAPGKGLEWVSVIYSGGSTFYADSVKGRFTISRDNSKNTLYL
QMNSLRAEDTAVYYCARDYGDYYFDYWGQGTLVTVSSASTKGPSVFPLAPSSKS(UNK)(UNK)(UNK)(UNK)TAALGC
LVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK

QVQLVESGGGLIQPGGSLRLSCAASGFIVSSNYMSWVRQAPGKGLEWVSVIYSGGSTFYADSVKGRFTISRDNSKNTLYL
QMNSLRAEDTAVYYCARDYGDYYFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSXXXXTAALGCLVKDYFPEPVTVSWNS
GALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK

EIVLTQSPGTLSLSPGERATLSCRASQSVSSSYLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLE
PEDFAVYYCQQYGSSPRTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNS
QESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE

National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)

Human Neutralizing Antibody, SARS-CoV-2, Receptor Binding Domain, COVID-19, IMMUNE SYSTEM