Crystal structure of PdGH110B D344N in complex with alpha-(1,3)-galactobiose

4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID

beta-D-galactose; D-galactose; galactose

alpha-D-galactose; D-galactose; galactose; ALPHA D-GALACTOSE

DICARBOXYLIC ACID C3; PROPANEDIOLIC ACID; METHANEDICARBOXYLIC ACID

(2R)-2-HYDROXYBUTANEDIOIC ACID; 2-HYDROXY-SUCCINIC ACID

The structure of a family 110 glycoside hydrolase provides insight into the hydrolysis of alpha-1,3-galactosidic linkages in lambda-carrageenan and blood group antigens.

MGSSHHHHHHSSGLVPRGSHMASNDKVIDVSDFGAIKDTGSDSTHSLYKALQEAKKIGATKITFPKGRYDFYEERAADRL
MYISNNDPGIKRITFPLSSFNNLEIDGNNSTFIFHGGLVPFILDESSHIVLRNFSIDFSRAFHSEALIAGAGKGYLDLKF
TDQFPYKINEAGILKFQSQLFQASGIKNKDRLKRKQISQDEYKYEYKRVLEFNFALREPEYMAQDIFTGNALRAEKLNGG
DVVRIFHPNLKAKVGNILVFQAKHRDYPGVVISDSNNVELHNITIHHAGGMGVIAQRSHNITIKDSKVSPSKGRIVSTTA
DATHFVNCTGKIKLIDNLFESQKNDATNIHGVYAAIDKIIDDKTVEIKLQHPQQFGFDFIAPEDELELVHGASLITYETN
KVVTSTRVSNEVTRVQFIKPFDSRIKEGDSVSKVRSYAEVIIKGNIIRKNRARGMLLNSRGKTLIENNYFHTPGSAILFE
GDANFWFEQGGVSDVTIKNNVFENSFYSQWGKGIIAVDAGIDDKFKETSRYNKNIVIKGNTFKVFDKAPILNLFSVSNLV
FENNIIEKTTEYPERKKYNSLFVINNSDNITISINNILQGFSEGKSQLLSPTTTYKRAKN

Natural Sciences and Engineering Research Council (NSERC, Canada)