Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex (conformation 2)

PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
ATP-GAMMA-S; ADENOSINE 5'-(3-THIOTRIPHOSPHATE); ADENOSINE 5'-(GAMMA-THIOTRIPHOSPHATE); ADENOSINE-5'-DIPHOSPHATE MONOTHIOPHOSPHATE

Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex.

MRLELPVIPLRNTVILPHTTTPVDVGRAKSKRAVEEAMGADRLIFLVAQRDPEVDDPAPDDLYTWGVQAVVKQAMRLPDG
TLQVMVEARARAQVTDYIPGPYLRARGEVFSEIFPIDEAVVRVLVEELKEAFEKYVANHKSLRLDRYQLEAVKGTSDPAM
LADTIAYHATWTVAEKQEILELTDLEARLKKVLGLLSRDLERFELDKRVAQRVKEQMDTNQREYYLREQMKAIQKELGGE
DGLSDLEALRKKIEEVGMPEAVKTKALKELDRLERMQQGSPEATVARTYLDWLTEVPWSKADPEVLDINHTRQVLDEDHY
GLKDVKERILEYLAVRQLTQGLDVRNKAPILVLVGPPGVGKTSLGRSIARSMNRKFHRISLGGVRDEAEIRGHRRTYIGA
MPGKLIHAMKQVGVINPVILLDEIDKMSSDWRGDPASAMLEVLDPEQNNTFTDHYLDVPYDLSKVFFITTANTLQTIPRP
LLDRMEVIEIPGYTNMEKQAIARQYLWPKQVRESGMEGRIEVTDAAILRVISEYTREAGVRGLERELGKIARKGAKFWLE
GAWEGLRTIDASDIPTYLGIPRYRPDKAETEPQVGTAQGLAWTPVGGTLLTIEVAAVPGSGKLSLTGQLGEVMKESAQAA
LTYLRAHTQDYGLPEDFYNKVDLHVHVPDGATPKDGPSAGITMATAIASALSRRPARMDIAMTGEVSLRGKVMPIGGVKE
KLLAAHQAGIHKIVLPKDNEAQLEELPKEVLEGLEIKLVEDVGEVLEYLLLPEPTMPPVVQPSDNRQQPGAGAKLAAALE
HHHHHH

(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)

Ministry of Science and Technology (MoST, Taiwan)

AAA, protease, complex, proteolysis, HYDROLASE

MRLELPVIPLRNTVILPHTTTPVDVGRAKSKRAVEEAMGADRLIFLVAQRDPEVDDPAPDDLYTWGVQAVVKQAMRLPDG
TLQVMVEARARAQVTDYIPGPYLRARGEVFSEIFPIDEAVVRVLVEELKEAFEKYVANHKSLRLDRYQLEAVKGTSDPAM
LADTIAYHATWTVAEKQEILELTDLEARLKKVLGLLSRDLERFELDKRVAQRVKEQMDTNQREYYLREQMKAIQKELGGE
DGLSDLEALRKKIEEVGMPEAVKTKALKELDRLERMQQGSPEATVARTYLDWLTEVPWSKADPEVLDINHTRQVLDEDHY
GLKDVKERILEYLAVRQLTQGLDVRNKAPILVLVGPPGVGKTSLGRSIARSMNRKFHRISLGGVRDEAEIRGHRRTYIGA
MPGKLIHAMKQVGVINPVILLDEIDKMSSDWRGDPASAMLEVLDPEQNNTFTDHYLDVPYDLSKVFFITTANTLQTIPRP
LLDRMEVIEIPGYTNMEKQAIARQYLWPKQVRESGMEGRIEVTDAAILRVISEYTREAGVRGLERELGKIARKGAKFWLE
GAWEGLRTIDASDIPTYLGIPRYRPDKAETEPQVGTAQGLAWTPVGGTLLTIEVAAVPGSGKLSLTGQLGEVMKESAQAA
LTYLRAHTQDYGLPEDFYNKVDLHVHVPDGATPKDGPSAGITMATAIASALSRRPARMDIAMTGEVSLRGKVMPIGGVKE
KLLAAHQAGIHKIVLPKDNEAQLEELPKEVLEGLEIKLVEDVGEVLEYLLLPEPTMPPVVQPSDNRQQPGAGA