Drosophila P5CS filament with glutamate and ATPgammaS

Structural basis of dynamic P5CS filaments.

Drosophila Delta-1-pyrroline-5-carboxylate synthase bound with ATP-gamma-S and Glutamate

Escherichia coli 'BL21-Gold(DE3)pLysS AG'

Delta-1-pyrroline-5-carboxylate synthase

MLQNSFKLAQSLRNGFYRNAWRAFSSHGPRQPLVSPERRLEKAHPTFTERSQLKYARRLVVKLGSAVITREDNHGLALGR
LASIVEQVAECHLEGREVMMVTSGAVAFGKQKLAQELLMSLSMRETLNPKDSKEFDGATLEPRAAAAVGQSGLMSLYDAM
FAQYGVKIAQVLVTKPDFYNEETRNNLFCTLSELISLNIVPIINTNDAVSPPMFIRDDEPAGGARRGIPIKDNDSLSAML
AAEVQADLLILMSDVDGIYNKPPWEDGAKLMHTYTSDDSNSIEFGKKSKVGTGGMDSKVKAATWALDRGVSVVICNGMQE
KAIKTIIGGRKVGTFFTEATESANAVPVEVMAENARTGSRQMQALTPAQRASAVNTLADLLVSREKFILDANAKDLAEAQ
KSGLAKPLLSRLSLNPAKLKNLSVGLKQIAEDSHKNVGRVLRRTRLADQLELKQVTVPIGVLLVIFESRPDSLPQVAALA
MASANGLLLKGGKEAAHSNKALMELVKEALATVGAEHAVSLVSTREEISDLLSMENHIDLIIPRGSSDLVRSIQQQSLHI
PVLGHAEGVCHVYIDRDADLEKALRIARDAKCDYPAACNAMETLLIHEDLMSGAIFGDVCNMLKREGVKIYAGPRLNQQL
TFGPPAAKSLKHEYGALECCIEVVPSLDEAINHIHTYGSSHTDVIVTENDAAARQFLGSVDSACVFHNASSRFADGFRFG
LGAEVGISTARIHARGPVGVEGLLTTKWILEGQDHAAADFAEGGGRTWLHETLPLD

National Natural Science Foundation of China (NSFC)

Structural basis of assembly and activity of P5CS filament

filament, ALDH18A1, Delta-1-pyrroline-5-carboxylate synthase, BIOSYNTHETIC PROTEIN, TRANSFERASE