Structural evolution of the tissue-specific U2AF2 paralog and alternative splicing factor LS2
SISVSAMESYRSFRVPAINVAQQPAVTLPVTTIVPDSPNKIYVGGLPTCLNQDQVKELLQSFGELKGLNLVMDTNTNLNK GFAFFEYCDPSVTDHAIAGLHGMLLGDRRLVVQRSIPGGKNA
1.0 mM [U-13C; U-15N] LS2 Linker RRM2, 0.02 mM [U-13C; U-15N] potassium phosphate, 0.05 mM [U-13C; U-15N] sodium chloride, 0.002 mM [U-13C; U-15N] DTT, 90% H2O/10% D2O
alternative splicing, structural biology, G quadruplex, U2AF, LS2, RRM RNA binding domain, RNA-protein interactions, RNA BINDING PROTEIN