The structure of a CoA-dependent acyl-homoserine lactone synthase, RpaI, with the adduct of SAH and p-coumaroyl CoA

(2S)-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl}sulfanyl)-2-{[(2E)-3-(cis-4-hydroxycyclohexa-2,5-dien-1-yl)prop-2-enoyl]amino}butanoic acid

Structure-Guided Biochemical Analysis of Quorum Signal Synthase Specificities.

p-coumaryl-homoserine lactone synthase,pC-HSL synthase,RpaI

MQVHVIRRENRALYAGLLEKYFRIRHQIYVVERGWKELDRPDGREIDQFDTEDAVYLLGVDNDDIVAGMRMVPTTSPTLL
SDVFPQLALAGPVRRPDAYELSRIFVVPRKRGEHGGPRAEAVIQAAAMEYGLSIGLSAFTIVLETWWLPRLVDQGWKAKP
LGLPQDINGFSTTAVIVDVDDDAWVGICNRRSVPGPTLEWRGLEAIRRHSLPE

HYDROGENS HAVE BEEN USED IF PRESENT IN THE INPUT U VALUES : REFINED INDIVIDUALLY

acyl-homoserine lactone, coenzyme A, RpaI, TRANSFERASE