2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.

1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.

N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE

The shared susceptibility epitope of HLA-DR4 binds citrullinated self-antigens and the TCR.

HLA class II histocompatibility antigen, DR alpha chain

HLA class II histocompatibility antigen, DRB1-4 beta chain

IKEEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYT
PITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLPSTEDV
YDCRVEHWGLDEPLLKHWEFDTSGDDDDK

GDTRPRFLEQVKHECHFFNGTERVRFLDRYFYHQEEYVRFDSDVGEYRAVTELGRPDAEYWNSQKDLLEQKRAAVDTYCR
HNYGVGESFTVQRRVYPEVTVYPAKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKTGVVSTGLIQNGDWTFQTLVM
LETVPRSGEVYTCQVEHPSLTSPLTVEWRATGGDDDDK

GDSVTQTEGPVTLSEGTSLTVNCSYETKQYPTLFWYVQYPGEGPQLLFKVPKANEKGSNRGFEATYNKEATSFHLQKASV
QESDSAVYYCALSPSNTNKVVFGTGTRLQVLPNIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKC
VLDMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDTFFPSPESS

AVFQTPNYHVTQVGNEVSFNCKQTLGHDTMYWYKQDSKKLLKIMFSYNNKQLIVNETVPRRFSPQSSDKAHLNLRIKSVE
PEDSAVYLCASSLDWGVNTLYFGAGTRLSVLEDLNKVFPPEVAVFEPSEAEISHTQKATLVCLATGFFPDHVELSWWVNG
KEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRA
D

chain 'A' and (resid 3 through 55 )

chain 'A' and (resid 56 through 133 )

chain 'A' and (resid 134 through 144 )

chain 'A' and (resid 145 through 180 )

chain 'B' and (resid 2 through 18 )

chain 'B' and (resid 19 through 51 )

chain 'B' and (resid 52 through 63 )

chain 'B' and (resid 64 through 89 )

chain 'B' and (resid 90 through 133 )

chain 'B' and (resid 134 through 149 )

chain 'B' and (resid 150 through 188 )

chain 'C' and (resid 69 through 81 )

chain 'D' and (resid 1 through 30 )

chain 'D' and (resid 31 through 56 )

chain 'D' and (resid 57 through 88 )

chain 'D' and (resid 89 through 125 )

chain 'D' and (resid 126 through 154 )

chain 'D' and (resid 155 through 192 )

chain 'D' and (resid 193 through 206 )

chain 'D' and (resid 207 through 217 )

chain 'E' and (resid 3 through 44 )

chain 'E' and (resid 45 through 120 )

chain 'E' and (resid 121 through 135 )

chain 'E' and (resid 136 through 173 )

chain 'E' and (resid 174 through 199 )

chain 'E' and (resid 200 through 256 )

HVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITN
VPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLPSTEDVYDCR
VEHWGLDEPLLKHWEFD

GDTRPRFLEQVKHECHFFNGTERVRFLDRYFYHQEEYVRFDSDVGEYRAVTELGRPDAEYWNSQKDLLEQKRAAVDTYCR
HNYGVGESFTVQRRVYPEVTVYPAKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKTGVVSTGLIQNGDWTFQTLVM
LETVPRSGEVYTCQVEHPSLTSPLTVEWRA