Single particle cryo-EM structure of KvAP

Cryo-EM structure of the KvAP channel reveals a non-domain-swapped voltage sensor topology.

MAGGRVRNIGDVMEHPLVELGVSYAALLSVIVVVVEYTMQLSGEYLVRLYLVDLILVIILWADYAYRAYKSGDPAGYVKK
TLYEIPALVPAGLLALIEGHLAGLGLFRLVRLLRFLRILLIISRGSKFLSAIADAADKIRFYHLFGAVMLTVLYGAFAIY
IVEYPDPNSSIKSVFDALWWAVVTATTVGYGDVVPATPIGKVIGIAVMLTGISALTLLIGTVSNMFQKILVGEPEPSSSP
AKLAEMVSSMSEEEFEEFVRTLKNLRRLENSMKLVPRGSRSHHHHHH

National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)

voltage-gated potassium channel, non-domain-swapped, TRANSPORT PROTEIN

GGRVRNIGDVMEHPLVELGVSYAALLSVIVVVVEYTMQLSGEYLVRLYLVDLILVIILWADYAYRAYKSGDPAGYVKKTL
YEIPALVPAGLLALIEGHLAGLGLFRLVRLLRFLRILLIISRGSKFLSAIADAADKIRFYHLFGAVMLTVLYGAFAIYIV
EYPDPNSSIKSVFDALWWAVVTATTVGYGDVVPATPIGKVIGIAVMLTGISALTLLIGTVSNMFQKILVGEPEPSCSPAK
LAEMVSSMSEEEFEEFVRTLKNLRRLENSMK