Crystal structure of a high molecular weight 3-oxoacyl-ACP reductase (FabG) from Acinetobacter baumannii crystal form 2

2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.

Insights into Acinetobacter baumannii fatty acid synthesis 3-oxoacyl-ACP reductases.

MHHHHHHSSGVDLGTENLYFQSNAMTDQYQAFTQSPIGKFVVKNLGLPSPVVLERFESAQPVVKGAVLVGAAPSSVLSGA
IAQVLSNIHTDSYVGNNVALQQEAAKVGLNLRPFNAGDKESKFKAVVFDASGIQNSEQLNELYKFFNPIARQVATSGRVI
VIGTTPETAKTVKQAIAQRALEGFIKSVGKEFKKGITAQVVYVDEGAAANLESTLRFLLSPRSAYVSGQVIRVSKADVVD
VDWAKPLAGKTALVTGASRGIGEAIAHVLARDGAHVICLDVPQQQADLDRVAADIGGSTLAIDITAADAGEKIKAAAAKQ
GGLDIIVHNAGITRDKTLANMKPELWDLVININLSAAERVNDYLLENDGLNANGRIVCVSSISGIAGNLGQTNYAASKAG
VIGLVKFTAPILKNGITINAVAPGFIETQMTAAIPFAIREAGRRMNSMQQGGLPVDVAETIAWFASTASTGVNGNVVRVC
GQSLLGA

0.2M sodium malonate pH4.0 + 20% PEG 3350

FabG, Reductase, HMw, 3-oxoacyl-ACP, OXIDOREDUCTASE

MTDQYQAFTQSPIGKFVVKNLGLPSPVVLERFESAQPVVKGAVLVGAAPSSVLSGAIAQVLSNIHTDSYVGNNVALQQEA
AKVGLNLRPFNAGDKESKFKAVVFDASGIQNSEQLNELYKFFNPIARQVATSGRVIVIGTTPETAKTVKQAIAQRALEGF
IKSVGKEFKKGITAQVVYVDEGAAANLESTLRFLLSPRSAYVSGQVIRVSKADVVDVDWAKPLAGKTALVTGASRGIGEA
IAHVLARDGAHVICLDVPQQQADLDRVAADIGGSTLAIDITAADAGEKIKAAAAKQGGLDIIVHNAGITRDKTLANMKPE
LWDLVININLSAAERVNDYLLENDGLNANGRIVCVSSISGIAGNLGQTNYAASKAGVIGLVKFTAPILKNGITINAVAPG
FIETQMTAAIPFAIREAGRRMNSMQQGGLPVDVAETIAWFASTASTGVNGNVVRVCGQSLLGA