Crystal structure of 2541 Fab in complex with circumsporozoite protein NANP5

2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.

Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs.

QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYGMHWVRQTTGKGLEWVAIIWHDGSKKYYADSVKGRLTISRDNSKNTLY
LQMNSLRVEDTALYYCARVGDYSDFKYGAFDIWGQGTMVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPV
TVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC

DIQMTQSPSTLSASVGDRVTITCRASQSISSWLAWYQQKPGKAPNLLIYKASTLESGVPSRFSGSGSGTEFTLTISSLQP
DDFATYYCQQYNSYWTFGQGTRVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQE
SVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC

1.8 M ammonium sulfate, 0.1 M citric acid pH 3.6