S2 symmetric peptide design number 6, London Bridge
3-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
Computational design of mixed chirality peptide macrocycles with internal symmetry.
The asymmetric unit contains half of the molecule. The second half is generated by a crystallographic symmetry operator.
0.1 M phosphate/citrate pH 4.2, 40% (v/v) PEG 300
Department of Energy (DOE, United States)
cyclic peptide, centrosymmetric macrocycle, L- and D-amino acids, DE NOVO PROTEIN