Crystal structure of human PD-1H / VISTA
Structural insight into T cell coinhibition by PD-1H (VISTA).
V-type immunoglobulin domain-containing suppressor of T-cell activation
Platelet receptor Gi24,Stress-induced secreted protein-1,Sisp-1,V-set domain-containing immunoregulatory receptor,V-set immunoregulatory receptor
FKVATPYSLYVCPEGQNVTLTCRLLGPVDKGHDVTFYKTWYRSSRGEVQTCSERRPIRNLTFQDLHLHHGGHQAANTSHD LAQRHGLESASDHHGNFSITMRNLTLLDSGLYCCLVVEIRHHHSEHRVHGAMELQVQTGKDAPSNCVVYPSSSQESENIT AVKLQAGFHHHHHH
VSIR, C10orf54, SISP1, VISTA, PP2135, UNQ730/PRO1412
0.3 ul protein in HBS with 0.3 ul of crystallization buffer consisting of 100 mM Bis-Tris:HCl pH 6.0 and 28% (v/v) polyethylene glycol monomethyl ether (MW 2000) (Sigma-Aldrich) under a drop of paraffin oil and silicon oil in a 2:1 ratio
HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS U VALUES : WITH TLS ADDED
T cell co-inhibition, immunoglobulin-like, IMMUNE SYSTEM
FKVATPYSLYVCPEGQNVTLTCRLLGPVDKGHDVTFYKTWYRSSRGEVQTCSERRPIRNLTFQDLHLHHGGHQAANTSHD LAQRHGLESASDHHGNFSITMRNLTLLDSGLYCCLVVEIRHHHSEHRVHGAMELQVQTGKDAPSNCVVYPSSSQDSENIT A