alpha-L-fucose; 6-deoxy-alpha-L-galactopyranose; L-fucose; fucose

N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE

Highly Conserved Molecular Features in IgLONs Contrast Their Distinct Structural and Biological Outcomes.

ELGTGVDFPWAAVDNMMVRKGDTAVLRCYLEDGASKGAWLNRSSIIFAGGDKWSVDPRVSISTLNKRDYSLQIQNVDVTD
DGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLATGKPEPSISWRHISPSAKPFENGQYLDIYG
ITRDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGII
IQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLNASTSHHHHHH

Baculovirus expression vector pFastBac1-HM

Protein: 2.5 mg/ml NEGR1 in 10 mM HEPES, pH 8.0, 150 mM NaCl. Reservoir Solution: 20% (w/v) PEG 3350, 0.1 M Tris pH 9.0, 0.2 M MgCl2, 0.6 M NaI. Crystallization Drop: 1 micro-Liter NEGR1 + 1 micro-Liter Reservoir Solution Single crystals were obtained via microseeding, and their size improved to ~600 x 200 micro-meters by macroseeding. Crystals harvested from the crystallization drops were cryo-protected in reservoir solution containing 20% (v/v) MPD and then flash cooled by plunging into liquid nitrogen

National Institutes of Health/National Institute of Mental Health (NIH/NIMH)

synaptic organizer, IgLON, Ig domain-containing, CELL ADHESION

(chain A and (resid 47 through 50 or resid 52 through 60 or resid 62 or resid 68 through 94 or resid 100 through 128 or resid 130 through 131 or resid 133 through 164 or resid 166 through 172 or resid 174 through 176 or resid 184 through 199 or resid 201 through 206 or resid 212 through 230 or resid 232 through 233 or resid 241 through 258 or resid 271 through 283 or resid 294 through 312 or (resid 313 and (name N or name CA or name C or name O or name CB or name CG or name OD1 or name ND2)) or resid 401 through 501))

(chain B and (resid 47 through 50 or resid 52 through 60 or resid 62 or resid 68 through 94 or resid 100 through 128 or resid 130 through 131 or resid 133 through 164 or resid 166 through 172 or resid 174 through 176 or resid 184 through 199 or resid 201 through 206 or resid 212 through 230 or resid 232 through 233 or resid 241 through 258 or resid 271 through 283 or resid 294 through 501))

VDFPWAAVDNMMVRKGDTAVLRCYLEDGASKGAWLNRSSIIFAGGDKWSVDPRVSISTLNKRDYSLQIQNVDVTDDGPYT
CSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLATGKPEPSISWRHISPSAKPFENGQYLDIYGITRDQ
AGEYECSAENDVSFPDVRKVKVVVNFAPTIQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFS
TRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLN