A New Structural Model of Abeta(1-40) Fibrils

Mixing A beta (1-40) and A beta (1-42) peptides generates unique amyloid fibrils.

A new structural model of Abeta40 fibrils.

APP,ABPP,APPI,Alzheimer disease amyloid protein,Amyloid precursor protein,Amyloid-beta A4 protein,Cerebral vascular amyloid peptide,CVAP,PreA4,Protease nexin-II,PN-II

100 uM [U-100% 13C; U-100% 15N] Amyloid beta peptide 1-40, 50 mM ammonium acetate, H2O
The fibrils were grown in ammonium acetate buffer and then washed with fresh, cold ultrapure water (Millipore) three times.

scanning transmission electron microscopy

amyloid beta peptides, Alzheimer's disease, supramolecular assembly, protein fibril