The Biosynthesis of the Benzoxazole in Nataxazole Proceeds via an Unstable Ester and has Synthetic Utility.

MSYYHHHHHHDYDIPTTENLYFQGAMGARLITGGTVYTADAQESVHARGAVLTVDDKVVAVGPAVEVEQAVQALDPAVRA
ELRRLDASRMMVLPGFVNAHWHEMFAMGFTMRGALRPPSDRADQVAFMGGGGDMHQISATFDRFDGLIEAMTEDEARAIA
EYSMWIQLRGGVTTLGDMGSLNRPLAMVEAARRLGMRFSASTWASDAVLAPDRSRFLRTRDADTVLASFEALLGAVAADP
TGRIRCRPNVSYVTNMTDELARGMAELVERHDLPFATHVGALRNEADAMRAYHGETGVRRLAEAGLVDERLMAGHSAFLD
DQEQKLMLAGRAHISHSPGKYGPSGESALTETGVVPALRRAGLDVSLSTDAAALPGAGIAETMRAAWQMYNEMSADQTEV
LPTDALAMATRIAAKGLRWDDAVGSLEPGKQADLLLVRTDDWRYLLNPRPLESFLWLAGSADVDTVIVGGRTLVEGGRGV
EVDEAALRDRYLQALRGFTTRALRVPAEAVDPVLAEVAR

0.2 M MgCl2, 0.1 M Bis-Tris pH 6.5 and 25% w/v polyethylene glycol 3,350

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS U VALUES : WITH TLS ADDED

MGARLITGGTVYTADAQESVHARGAVLTVDDKVVAVGPAVEVEQAVQALDPAVRAELRRLDASRMMVLPGFVNAHWHEMF
AMGFTMRGALRPPSDRADQVAFMGGGGDMHQISATFDRFDGLIEAMTEDEARAIAEYSMWIQLRGGVTTLGDMGSLNRPL
AMVEAARRLGMRFSASTWASDAVLAPDRSRFLRTRDADTVLASFEALLGAVAADPTGRIRCRPNVSYVTNMTDELARGMA
ELVERHDLPFATHVGALRNEADAMRAYHGETGVRRLAEAGLVDERLMAGHSAFLDDQEQKLMLAGRAHISHSPGKYGPSG
ESALTETGVVPALRRAGLDVSLSTDAAALPGAGIAETMRAAWQMYNEMSADQTEVLPTDALAMATRIAAKGLRWDDAVGS
LEPGKQADLLLVRTDDWRYLLNPRPLESFLWLAGSADVDTVIVGGRTLVEGGRGVEVDEAALRDRYLQALRGFTTRALRV
PAEAVDPVLAEVAR