LXRbeta ligand binding domain in comlpex with small molecule inhibitors

Structural analysis identifies an escape route from the adverse lipogenic effects of liver X receptor ligands.

KVK A 501 HAS WRONG CHIRALITY AT ATOM C5

KVK B 501 HAS WRONG CHIRALITY AT ATOM C5

KVK C 501 HAS WRONG CHIRALITY AT ATOM C5

Liver X receptor beta,Nuclear receptor NER,Nuclear receptor subfamily 1 group H member 2,Ubiquitously-expressed nuclear receptor

GVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLG
REDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAI
NIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEI
WDVHE

Hydrogens have been added in their riding positions

liver X receptor beta LXRb LXR beta Nuclear hormone receptor receptor ligand binding domain, nuclear protein