Structure of Aedes aegypti OBP22 in the complex with benzaldehyde
Aedes aegypti Odorant Binding Protein 22 selectively binds fatty acids through a conformational change in its C-terminal tail.
MEFTVSTTEDLQRYRTECVSSLNIPADYVEKFKKWEFPEDDTTMCYIKCVFNKMQLFDDTEGPLVDNLVHQLAHGRDAEE VRTEVLKCVDKNTDNNACHWAFRGFKCFQKNNLSLIKASIKKD
2M Ammonium sulfate, 0.1 M sodium citrate, 0.2M sodium potassium tartrate
National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)
Structure of AeOBP22 bound to linoleic acid
Structure of AeOBP22 bound to arachidonic acid
Structure of AeOBP22 bound to palmitoleic acid
Structure of AeOBP22 bound to arachidic acid
NMR relaxation experiments establish the overall correlation time is consistent with the presence of a monomeric species in solution. The dimeric form appears to be a crystallization artifact.
Odorant binding protein, Chemo-sensory signaling, TRANSPORT PROTEIN
EFTVSTTEDLQRYRTECVSSLNIPADYVEKFKKWEFPEDDTTMCYIKCVFNKMQLFDDTEGPLVDNLVHQLAHGRDAEEV RTEVLKCVDKNTDNNACHWAFRGFKCFQKNNLSLIKASIKKD