Crystal Structure of Aspergillus fumigatus Ega3

N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE

Ega3 from the fungal pathogenAspergillus fumigatusis an endo-alpha-1,4-galactosaminidase that disrupts microbial biofilms.

GSHMGLGGGGGGEGEEGSGGETTPPEGNYTTAKWQPAVGTKWQIELLYALNDTSVDAEIYDIDLFINDKSTIAGLQRAGR
KVICYFSAGSYENWRPDKDKFKDSDLGHDLDDWPGEKWLNISSANVRQIMLDRLDMARDKGCDGVDPDNVDGYDNDNGLD
LTQADSISFVNFLANAAHARNMSIGLKNAGDIIPSVIKNMQWSVNEQCAQYNECDTYAVFPQNGKPVFHIEYPKGDKTNN
DLSVTASQKNAACDFAGSANFSTVIKNMNLNNWVEYC

Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)

0.2 M potassium iodide, 20 % (v/v) PEG 3350

Canadian Institutes of Health Research (CIHR)

galactosaminidase, (beta/alpha)-barrel, glycoside hydrolase, HYDROLASE

GLGGGGGGEGEEGSGGETTPPEGNYTTAKWQPAVGTKWQIELLYALNDTSVDAEIYDIDLFINDKSTIAGLQRAGRKVIC
YFSAGSYENWRPDKDKFKDSDLGHDLDDWPGEKWLNISSANVRQIMLDRLDMARDKGCDGVDPDNVDGYDNDNGLDLTQA
DSISFVNFLANAAHARNMSIGLKNAGDIIPSVIKNMQWSVNEQCAQYNECDTYAVFPQNGKPVFHIEYPKGDKTNNDLSV
TASQKNAACDFAGSANFSTVIKNMNLNNWVEYC