Crystal structure of the TIR domain from human SARM1 in complex with ribose

beta-D-ribose; D-ribose; ribose; BETA-D-RIBOFURANOSYL

NAD+cleavage activity by animal and plant TIR domains in cell death pathways.

Sterile alpha and TIR motif-containing protein 1

Sterile alpha and Armadillo repeat protein,Sterile alpha motif domain-containing protein 2,SAM domain-containing protein 2,Tir-1 homolog

SNADTPDVFISYRRNSGSQLASLLKVHLQLHGFSVFIDVEKLEAGKFEDKLIQSVMGARNFVLVLSPGALDKCMQDHDCK
DWVHKEIVTALSCGKNIVPIIDGFEWPEPQVLPEDMQAVLTFNGIKWSHEYQEATIEKIIRFLQ

0.1 M Bis Tris propane pH 6.5, 0.2 M potassium thiocyanate, 11% PEG3350

National Health and Medical Research Council (NHMRC, Australia)

DTPDVFISYRRNSGSQLASLLKVHLQLHGFSVFIDVEKLEAGKFEDKLIQSVMGARNFVLVLSPGALDKCMQDHDCKDWV
HKEIVTALSCGKNIVPIIDGFEWPEPQVLPEDMQAVLTFNGIKWSHEYQEATIEKIIRFLQ