X-ray structure of a secreted C11 cysteine protease from Bacteroides thetaiotaomicron "iotapain

X-ray Structures of Two Bacteroides thetaiotaomicron C11 Proteases in Complex with Peptide-Based Inhibitors.

Residues ARG A 171 and TYR A 173 that are next to each other in the sample sequence are not properly linked: distance between C and N is 33.01. Residues ARG B 171 and TYR B 173 that are next to each other in the sample sequence are not properly linked: distance between C and N is 32.91.

GEEPVPVPTEQTVFMYLPWSDNLTSNFYQNISDLESVVEKNILKDERIIIFMCTTATKATLFELAYENGKSVHKTLKNYT
DPAYTTAEGITSILNDVQRYSPTKRYSMVIGCHGMGWIPVSNSKSASGLRTKMHWEYENVPMTRYFGGLNAQYQTDITTL
AKGISNAGLKMEYILFDDCYMSSIEVAYALKDVTDYLIGSTSEVMAYGMPYAEIGQYLIGKVDYAGICDGFYSFYSTYST
PCGTIAVTDCSELDNLATIMKEINHRYTFDPSLTSSLQRLDGYYPVIFFDYGDYVSKLCPDETLVARFNEQLNRTVPFKR
NTEYFYSMSRGEVKINTFSGITISDPSTHSLASKKEETAWYAATH

Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)

0.1 M Na Citrate, pH 5.0, 50% MPD, 10 mM L-Proline

C11 protease, secreted, microbiome, commensal, HYDROLASE

EEPVPVPTEQTVFMYLPWSDNLTSNFYQNISDLESVVEKNILKDERIIIFMCTTATKATLFELAYENGKSVHKTLKNYTD
PAYTTAEGITSILNDVQRYSPTKRYSMVIGCHGMGWIPVSNSKSRSGLRTKMHWEYENVPMTRYFGGLNAQYQTDITTLA
KGISNAGLKMEYILFDDCYMSSIEVAYALKDVTDYLIGSTSEVMAYGMPYAEIGQYLIGKVDYAGICDGFYSFYSTYSTP
CGTIAVTDCSELDNLATIMKEINHRYTFDPSLTSSLQRLDGYYPVIFFDYGDYVSKLCPDETLVARFNEQLNRTVPFKRN
TEYFYSMSRGEVKINTFSGITISDPSTHSLASKKEETAWYAATH