NMR solution structure of Protonectin (Agelaia pallipes pallipes) interacting with SDS micelles: an antimicrobial peptide with anticancer activity on breast cancer cells
Protonectin peptides target lipids, act at the interface and selectively kill metastatic breast cancer cells while preserving morphological integrity.
1 mM Protonectin, 100 mM Perdeuterated SDS, 90% H2O/10% D2O
Brunger, Adams, Clore, Gros, Nilges and Read
Anticancer activity, Peptide membrane interaction, Protonectin aggregation surface interaction, ANTITUMOR PROTEIN