Relaxed state of S65/T66 double-phosphorylated ubiquitin
Ubiquitin is double-phosphorylated by PINK1 for enhanced pH-sensitivity of conformational switch.
MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKE(SEP)(TPO)LHLVLR LRGG
Ministry of Science and Technology (China)
National Natural Science Foundation of China
20 mM HEPES, 150 mM sodium chloride, 90% H2O/10% D2O
Schwieters, Kuszewski, Tjandra and Clore
phosphorylation, ubiquitin, pH-sensor, SIGNALING PROTEIN