structure of RET G-quadruplex in complex with berberine
Colchicine selective interaction with oncogene RET G-quadruplex revealed by NMR.
Solution structure of all parallel G-quadruplex formed by the oncogene RET promoter sequence.
DNA (5'-D(*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*GP*GP*GP*GP*T)-3')
the chemical shifts of free RET G-quadruplex
1.4 mM RET G4-DNA, 1.68 mM BERBERINE, 20 mM Potassium Phosphate Monobasic, 80 mM potassium chloride, 90% H2O/10% D2O
Delaglio, Grzesiek, Vuister, Zhu, Pfeifer and Bax
Schwieters, Kuszewski, Tjandra and Clore
one-dimensional NMR detected the Hoogsteen hydrogen bonds formed in G-quadruplex