Structure of human erythroid-specific 5'-aminolevulinate synthase, ALAS2

5-aminolevulinate synthase, erythroid-specific, mitochondrial

ALAS-E,5-aminolevulinic acid synthase 2,Delta-ALA synthase 2,Delta-aminolevulinate synthase 2

MGHHHHHHSSGVDLGTENLYFQSMFSYDQFFRDKIMEKKQDHTYRVFKTVNRWADAYPFAQHFSEASVASKDVSVWCSND
YLGMSRHPQVLQATQETLQRHGVGAGGTRNISGTSKFHVELEQELAELHQKDSALLFSSCFVANDSTLFTLAKILPGCEI
YSDAGNHASMIQGIRNSGAAKFVFRHNDPDHLKKLLEKSNPKIPKIVAFETVHSMDGAICPLEELCDVSHQYGALTFVDE
VHAVGLYGSRGAGIGERDGIMHKIDIISGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFTTSLPPMVLSGALESVRLL
KGEEGQALRRAHQRNVKHMRQLLMDRGLPVIPCPSHIIPIRVGNAALNSKLCDLLLSKHGIYVQAINYPTVPRGEELLRL
APSPHHSPQMMEDFVEKLLLAWTAVGLPLQDVSVAACNFCRRPVHFELMSEWERSYFGNMGPQYVTTYA

0.1M bis-tris pH 6.7, 25% PEG3350, 0.3M magnesium chloride

5-aminolevulinate synthase, erythroid-specific, Mitochondrial, Structural Genomics, Structural Genomics Consortium, SGC, oxidoreductase

(chain B and (resid 137 through 145 or (resid 146 through 147 and (name N or name CA or name C or name O or name CB )) or resid 148 through 153 or (resid 154 and (name N or name CA or name C or name O or name CB or name CG )) or resid 155 through 165 or (resid 166 and (name N or name CA or name C or name O or name CB or name CG or name CD )) or resid 167 through 182 or (resid 189 and (name N or name CA or name C or name O or name CB )) or resid 190 through 247 or resid 249 through 311 or (resid 312 and (name N or name CA or name C or name O or name CB or name CG or name CD )) or resid 313 through 379 or resid 381 through 454 or (resid 455 and (name N or name CA or name C or name O or name CB )) or resid 456 through 458 or (resid 459 and (name N or name CA or name C or name O or name CB or name CG )) or (resid 460 and (name N or name CA or name C or name O or name CB )) or resid 461 through 487 or (resid 488 and (name N or name CA or name C or name O or name CB )) or resid 489 through 529 or (resid 530 and (name N or name CA or name C or name O or name CB )) or resid 531 through 533 or (resid 534 through 535 and (name N or name CA or name C or name O or name CB )) or resid 536 through 576 or (resid 577 and (name N or name CA or name C or name O or name CB )) or resid 578 or resid 4701))

(chain D and (resid 137 through 146 or (resid 147 and (name N or name CA or name C or name O or name CB )) or resid 148 through 149 or (resid 150 and (name N or name CA or name C or name O or name CB or name CG or name CD )) or resid 151 or (resid 152 and (name N or name CA or name C or name O or name CB or name CG or name CD )) or resid 153 through 209 or (resid 210 through 211 and (name N or name CA or name C or name O or name CB )) or resid 212 through 213 or (resid 214 and (name N or name CA or name C or name O or name CB )) or resid 215 through 244 or (resid 245 and (name N or name CA or name C or name O or name CB or name CG )) or resid 246 through 247 or resid 249 through 310 or (resid 311 and (name N or name CA or name C or name O or name CB or name CG )) or resid 312 through 315 or (resid 316 and (name N or name CA or name C or name O or name CB )) or resid 317 through 319 or (resid 320 and (name N or name CA or name C or name O or name CB )) or resid 321 through 379 or resid 381 through 403 or (resid 404 and (name N or name CA or name C or name O or name CB or name CG or name CD )) or resid 405 through 534 or (resid 535 and (name N or name CA or name C or name O or name CB )) or resid 536 through 548 or (resid 558 through 559 and (name N or name CA or name C or name O or name CB )) or resid 560 through 578 or resid 2101))

FSYDQFFRDKIMEKKQDHTYRVFKTVNRWADAYPFAQHFSEASVASKDVSVWCSNDYLGMSRHPQVLQATQETLQRHGAG
AGGTRNISGTSKFHVELEQELAELHQKDSALLFSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKFVF
RHNDPDHLKKLLEKSNPKIPKIVAFETVHSMDGAICPLEELCDVSHQYGALTFVDEVHAVGLYGSRGAGIGERDGIMHKI
DIISGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFTTSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVKHMRQLLM
DRGLPVIPCPSHIIPIRVGNAALNSKLCDLLLSKHGIYVQAINYPTVPRGEELLRLAPSPHHSPQMMEDFVEKLLLAWTA
VGLPLQDVSVAACNFCRRPVHFELMSEWERSYFGNMGPQYVTTYA