Intercalation of [Ru(TAP)2(11-Br-dppz)]2+ bound to d(TCGGCGCCGA)2
Ruthenium (bis-(tetraazaphenanthrene)) (11-bromo-dipyridophenazine)
X-ray Crystal Structures Show DNA Stacking Advantage of Terminal Nitrile Substitution in Ru-dppz Complexes.
125 uM d(TCGGCGCCGA)2, 750 uM rac-[Ru(TAP)2(11-CN-dppz)]Cl2, 7.5% v/v MPD, 30 mM pH 7 sodium cacodylate, 9 mM spermine tetrahydrochloride, 60 mM KCl and 15 mM BaCl2, all equilibrated against 500 uL of 35% v/v MPD.
Biotechnology and Biological Sciences Research Council
DNA (5'-D(*TP*CP*GP*GP*CP*GP*CP*CP*GP*A)-3')
Ruthenium, intercalation, DNA, asymmetric