Crystal Structure of the Amyloid-like LNIYQY segment from the R1 repeat of the E. coli Biofilm-associated CsgA Curli protein
Structural Insights into Curli CsgA Cross-beta Fibril Architecture Inspire Repurposing of Anti-amyloid Compounds as Anti-biofilm Agents.
PETRA III, EMBL c/o DESY BEAMLINE P14 (MX2)
Amyloid spine segment LNIYQY from CsgA (residues 45-50) secreted by E. coli
Reservoir contained 0.1 M HEPES pH 7.5, 20% v/v Jeffamine M-600, 10 mM of the TAIVVQ peptide
HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS U VALUES : REFINED INDIVIDUALLY
Bacterial steric-zipper cross-beta amyloid fibril from E. coli, PROTEIN FIBRIL