Structural Basis of Phosphatidic Acid Sensing by APH in Apicomplexan Parasites.
SASDIRMKKVMQYRRALTKVVKLKTHLFSETVKVTCSKDGEEVQWFKGKSTAGAQDRKKPSGGFPVDKITSVKSQADNTK VLVITVNNPQPTTYNFTFKSPGERESWQEQIQSLMKFMSMK
Toxoplasma gondii (strain ATCC 50611 / Me49)
730 uM [U-100% 15N]; [U-100% 13C] C-terminal PH domain from TgAPH, 90% H2O/10% D2O
Purifies as a single monomer under reducing conditions
PH domain, phosphatidic acid binding, membrane association, LIPID BINDING PROTEIN