Lipoaminopeptide helioferin A and B from Mycogone rosea
(2S, 4S, 6S)-2-amino-6-hydroxy-4-methyl-8-oxodecanoic acid
MOO is 2-methyl-N-1-oxooctanoic acid,AMO is AHMOD is (2S, 4S, 6S)-2-amino-6-hydroxy-4-methyl-8-oxodecanoyl,AIB is alpha-aminoisobutyric acid,C9K is APAE is conformation A 2-(2-aminopropyl)aminoethanol and C9N, conformation B AMAE is 2-[(2-aminopropyl)-methylamino]-ethanol
The last amino alcohol residue is Apae in helioferin A and Amae in helioferin B. The deposited structure is neutral The presence of a proton at N2 of the last residue Apae/Amae is implicated.
Lipoaminopeptide, protonophoric, peptaibol, peptaibiotic, Antibiotic
binding site for residues AIB A 7 and AIB A 8
binding site for residues AIB A 8 and C9N A 9
binding site for residues AIB A 8 and C9K A 9