Crystal structure of a class I PreQ1 riboswitch complexed with a synthetic compound 3: 2-[(9H-carbazol-3-yl)oxy]-N,N-dimethylethan-1-amine
Synthetic ligands for PreQ1riboswitches provide structural and mechanistic insights into targeting RNA tertiary structure.
0.1 M potassium sodium tartrate, 0.1 M sodium citrate (pH 5.6), 2.8 M ammonium sulfate
National Institutes of Health/National Heart, Lung, and Blood Institute (NIH/NHLBI)
National Institutes of Health/National Cancer Institute (NIH/NCI)
Japan Society for the Promotion of Science (JSPS)
Caldanaerobacter subterraneus subsp. tengcongensis
PreQ1 riboswitch, Synthetic compound, Complex, RNA